Wednesday, December 6
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7:00 am - 8:00 am
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #2
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8:00 am - 8:15 am
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BREAK
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8:15 am - 8:30 am
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Welcome and Opening Remarks, Hall 4
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8:30 am - 9:00 am
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William L. McGuire Memorial Lecture, Hall 4
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9:00 am - 12:00 pm
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GENERAL SESSION 1, Hall 4
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12:00 pm
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EXHIBITS OPEN, Halls 1-2
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12:00 pm - 2:00 pm
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POSTER SESSION 1, Halls 1-2
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1:00 pm - 2:00 pm
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CONCURRENT SESSIONS
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Debate: Anthracyclines…To give or not to give? Stars at Night Ballroom 1-2
Moderator: Harold J. Burstein, Dana-Farber Cancer Institute, Boston, Massachusetts
“For”
Martine J. Piccart, Institut Jules Bordet, Brussels, Belgium
“Against”
Virginia F. Borgers, University of Colorado Anshutz Medical Campus, Aurora, Colorado
State-of-the-Art Session 1: Immunotherapy: Purpose, Resistance, and Toxicity, Stars at Night Ballroom 1-2
Moderator: Sherene Loi, Peter MacCallum Cancer Centre, Melbourne, Australia
Biomarkers predicting immune related adverse events
Toni K. Choueiri, Dana-Farber Cancer Institute, Boston, Massachusetts
Cellular therapies: What is the outlook for breast and other solid cancers?
Valentina Hoyos Velez, Baylor College of Medicine, Houston, Texas
Tumor mechanisms of resistance to immunotherapy
Sherene Loi, Peter MacCallum Cancer Centre, Melbourne, Australia
Chromosomal instability & resistance to immunotherapy
Kevin Litchfield, University College London, London, England
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2:00 pm - 3:00 pm
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Molecular Tumor Board, Hemisfair Ballroom 1-2
Moderator: Pedram Razavi, Memorial Sloan Kettering Cancer Center, New York, New York
Panelists:
Giuseppe Curigliano, European Institute of Oncology, Milan, Italy
Gaorav Gupta, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Celina G. Kleer, University of Michigan, Ann Arbor, Michigan
Nancy U. Lin, Dana-Farber Cancer Institute, Boston, Massachusetts
Elizabeth A. Morris UC Davis School of Medicine, Sacramento, California
Joyce A. O'shaughnessy, Baylor University Medical Center, Dallas, Texas
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3:00 pm - 5:00 pm
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CONCURRENT EDUCATIONAL SESSION BLOCK #2
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ED05: Controversies in Local Regional Management, Hemisfair Ballroom 1-2
Moderator: Debra Patt, Texas Oncology, Austin, Texas
Demystifying the axilla: Challenging scenarios in the upfront surgery setting and after neoadjuvant chemotherapy
Andrea V. Barrio, Memorial Sloan Kettering Cancer Center, New York, New York
When less is more: Patient-friendly radiation courses with WBI and PBI
Icro Meattini, Università degli Studi di Firenze, Florence, Italy
Surgical management of clinical stage I HER 2+ and triple negative breast cancer
Anita Mamtani, Memorial Sloan Kettering Cancer Center, New York, New York
Speaker to be announced
Panelist: Jamie LaScala, Translational Center of Excellence in Breast Cancer, Penn Medicine, Philadelphia, Pennsylvania
ED06: Coordinated Care of Brain Metastasis, Hemisfair Ballroom 3
Moderator: Carey K. Anders, Duke University Comprehensive Cancer Center, Durham, North Carolina
Speakers:
Rebecca Dent, National Cancer Centre Singapore, Singapore
Christopher D. Lascola, Duke University Medical Center, Durham, North Carolina
Nelson Moss, Memorial Sloan Kettering Cancer Center, New York, New York
Helen A. Shih, Massachusetts General Hospital, Boston, Massachusetts
Jeffrey Wefel, UT MD Anderson Cancer Center, Houston, Texas
ED07: HER2+ Breast Cancer: Updates from the Clinic and the Lab, Stars at Night Ballroom 1-2
Moderator: Mothaffar F. Rimawi, Baylor College of Medicine, Houston, Texas
Molecular determinates of response and resistance in HER2+ breast cancer
Ron Bose, Washington University School of Medicine in St. Louis, St. Louis, Missouri
Recent advances in systemic disease
Sherene Loi, Peter MacCallum Cancer Centre, Melbourne, Australia
Management of brain metastases
Sarah L. Sammons, Dana-Farber Cancer Institute, Boston, Massachusetts
Panelist: Terlisa Sheppard, Terlisa Fights Breast Cancer, Inc., Florida
ED08: Toxicity Management: Next-Gen Therapies Means Next-Gen Toxicities, Stars at Night Ballroom 3-4
Moderator: Antonio C. Wolff, Johns Hopkins University, Baltimore, Maryland
Antibody drug conjugates
Heather L. McArthur, UT Southwestern Medical Center, Dallas, Texas
Targeted therapeutics in hormone positive breast cancers
Erica L. Mayer, Dana-Farber Cancer Institute, Boston, Massachusetts
Immunotherapies – short and long term
Douglas B. Johnson, Vanderbilt University Medical Center, Nashville, Tennessee
Panelist: Sheila Johnson, Komen Advocates in Science, Swansea, Illinois
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5:00 pm - 7:00 pm
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POSTER SESSION 2, Halls 1-2
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5:30 pm - 6:30 pm
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #3
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7:00 pm
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EXHIBITS CLOSE, Halls 1-2
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Thursday, December 7
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7:00 am - 8:00 am
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #4
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8:00 am - 8:15 am
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BREAK
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8:15 am - 11:15 am
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General Session 2, Hall 4
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11:15 am - 11:45 am
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Plenary Lecture 1, Hall 4
Tumor heterogeneity and evolution in breast cancer
Charles Swanton, The Francis Crick Institute, London, England
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1145 am - 12:00 pm
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BREAK
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12:00 pm
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EXHIBITS OPEN, Halls 1-2
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12:00 pm - 2:00 pm
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POSTER SESSION 3, Halls 1-2
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1:00 pm - 1:30 pm
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AACR Distinguished Lectureship in Breast Cancer Research, supported by Aflac Inc., Stars at Night Ballroom 1-2
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1:00 pm - 2:00 pm
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CONCURRENT SESSIONS
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Clinical Case Discussions, Stars at Night Ballroom 3-4
Moderator: Matthew P. Goetz, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
Panelists:
Fabrice André, Gustave Roussy, Villejuif, France
Nadia Harbeck, LMU University Hospital, Munich, Germany
Erica L. Mayer, Dana-Farber Cancer Institute, Boston, Massachusetts
Aleix Prat, Hospital Clínic Barcelona, Barcelona, Spain
Hope S. Rugo, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
State-of-the-Art Session 2: Implications of Senescence for Breast Cancer Biology and Treatment, Hemisfair Ballroom 1-2
Moderator: Justin M. Balko, Vanderbilt University, Nashville, Tennessee
Speaker to be announced
Implications of therapy induced senescence in breast cancer
James G. Jackson, Tulane University School of Medicine, New Orleans, Louisiana
Clinical trials and new therapeutics
Shom Goel, Peter MacCallum Cancer Centre, Melbourne, Australia
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2:00 pm - 3:00 pm
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Clinical Controversies, Stars at Night Ballroom 3-4
Moderator: Lisa A. Carey, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Are we ready to stop staging the axilla?
Monica Morrow, Memorial Sloan Kettering Cancer Center, New York, New York
Armando E. Giuliano, Cedars-Sinai Medical Center, Los Angeles, California
How to treat small triple negative breast cancer
Priyanka Sharma, University of Kansas Medical Center, Kansas City, Kansas
Alexandra Thomas, Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
Biology or stage? Tailoring treatment for premenopausal women with nodal involvement, but low oncotype
Eric P. Winer, Yale Cancer Center, New Haven, Connecticut
Kevin M. Kalinsky, Emory Winship Cancer Institute, Atlanta, Georgia
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3:00 pm - 5:00 pm
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CONCURRENT EDUCATIONAL SESSION BLOCK #3
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ED09: Genomics for the Clinician, Stars at Night Ballroom 3-4
Moderator: Norah Lynn Henry, Rogel Cancer Center University of Michigan, Ann Arbor, Michigan
Speaker to be announced
Tumor tissue vs. ctDNA
Ben O'Leary, Royal Marsden Hospital, London, England
When do you order and how to interpret genomic testing
Jorge S. Reis-Filho, Memorial Sloan Kettering Cancer Center, New York, New York
ED10: PI(3)king the Right Target, Stars at Night Ballroom 3-4
Moderator: Cynthia X. Ma, Washington University Siteman Cancer Center, Saint Louis, Missouri
PI3 Kinase
Neil Vasan, Columbia University Irving Medical Center, New York, New York
AKT pathway
Alex Toker, Beth Israel Deaconess Medical Center, Boston, Massachusetts
mTOR pathway
Robert J. Schneider, NYU Grossman School of Medicine, New York, New York
ED11: Inflammatory Breast Cancer: Clinical Challenges, Evolving Concepts and Novel treatments (People’s Choice), Hemisfair Ballroom 1-2
Moderator and Speakers to be announced
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5:00 pm - 7:00 pm
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POSTER SESSION 4, Halls 1-2
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5:30 pm - 6:30 pm
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #5
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7:00 pm
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EXHIBITS CLOSE, Halls 1-2
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Friday, December 8
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7:00 am - 8:00 am
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #6
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8:00 am - 8:15 am
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BREAK
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8:15 am - 11:15 am
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General Session 3, Hall 4
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11:15 am - 11:45 am
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Plenary Lecture 2, Hall 4
Recent advances in triple negative breast cancer
Melinda L. Telli, Stanford University School of Medicine, Stanford, California
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11:45 am - 12:00 pm
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BREAK
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12:00 pm
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EXHIBITS OPEN, Halls 1-2
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12:00 pm - 2:00 pm
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POSTER SESSION 5, Halls 1-2
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1:00 pm - 1:30 pm
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AACR Outstanding Investigator Award for Breast Cancer Research, supported by the Breast Cancer Research Foundation, Stars at Night Ballroom 1-2
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1:30 pm - 2:30 pm
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CONCURRENT SESSIONS
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Translational Research Controversies, Stars at Night Ballroom 3-4
Moderator: Komal Jhaveri, Memorial Sloan Kettering Cancer Center, New York, New York
Baby-TAM
Per Hall, Karolinska Institutet, Stockholm, Sweden
Jack Cuzick, Queen Mary University of London, London, England
When to do a window trial
Mitchell Dowsett, Royal Marsden Hospital, London, England
Sara A. Hurvitz, UCLA – University of California Los Angeles, Los Angeles, California
Are we sequencing too late?
Charles M. Perou, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Fabrice André, Gustave Roussy, Villejuif, France
State-of-the-Art Session 3: Targeting Mutant ER, Hemisfair Ballroom 1-2
Moderator: Aditya Bardia, Massachusetts General Hospital, Boston, Massachusetts
Biological consequences of ESR1 mutation
Geoffrey L. Greene, University of Chicago, Chicago, Illinois
Tracking mutant ER using ctDNA
François-Clément Bidard, Institut Curie, Paris, France
The future of oral SERDs
Erika P. Hamilton, Sarah Cannon Research Institute, Nashville, Tennessee
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2:30 pm - 2:45 pm
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BREAK
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2:45 pm - 3:45 pm
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Year in Review, Hall 4
Moderator: Carlos L. Arteaga, UT Southwestern Harold C. Simmons Comprehensive Cancer Center, Dallas, Texas
Advanced Breast Cancer
Mariana Chavez-Mac Gregor, UT MD Anderson, Houston, Texas
Early Breast Cancer
Ann H. Partridge, Dana-Farber Cancer Institute, Boston, Massachusetts
Basic Science
Heide L. Ford, University of Colorado Denver School of Medicine, Denver, Colorado
Translational
Jennifer K. Richer, University of Colorado Anshutz Medical Campus, Aurora, Colorado
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3:45 pm - 4:00 pm
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BREAK
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4:00 pm
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Exhibits Close, Hall 1-2
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4:00 pm - 6:00 pm
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View from the Trenches: What will You do on Monday Morning? Hall 4
Moderator: Sara M. Tolaney, Dana-Farber Cancer Institute, Boston, Massachusetts
Panelists:
Javier Cortes Castan, Ramón y Cajal University Hospital, Madrid, Spain
Lesley Glenn, Project Life, Central Point, Oregon
Sara A. Hurvitz, University of California Los Angeles, Los Angeles, California
Joyce A. O'Shaughnessy, Baylor University Medical Center, Dallas, Texas
Richard C. Zellars, Indiana University School of Medicine, Indianapolis, Indiana
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Saturday, December 9
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7:00 am - 11:00 am
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Career Development Day
Details to be announced
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