Wednesday, December 6
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7:00 am - 8:00 am
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #2
PS4 Gaps
in the Timing, Treatment Selection, and Supportive Services for Cancer
Care, Stars at Night Ballroom 3-4,
PS5 Shining a New Light on Breast Cancer: Novel Molecular and
Functional Imaging Approaches to Detect and Characterize Breast Cancer, Hemisfair Ballroom 1-2
PS6 Prognostic and Predictive uses of cell free DNA, Stars at Night Ballroom 1-2
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8:00 am - 8:15 am
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BREAK
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8:15 am - 8:30 am
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Welcome and Opening Remarks, Hall 1
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8:30 am - 9:00 am
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William L. McGuire Memorial Lecture, Hall 1
Jack Cuzick, Queen Mary University of London, London, England
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9:00 am - 12:00 pm
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GENERAL SESSION 1, Hall 1
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12:00 pm
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EXHIBITS OPEN, Halls 2-3 |
12:00 pm - 2:00 pm
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POSTER SESSION 1, Halls 2-3
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12:00 pm - 1:00 pm |
Rapid Fire: Mini-Oral Presentations, Hemisfair Ballroom 1-2 |
1:00 pm - 2:00 pm
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CONCURRENT SESSIONS
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Debate: Anthracyclines…To give or not to give? Stars at Night Ballroom 1-2
Moderator: Harold J. Burstein, Dana-Farber Cancer Institute, Boston, Massachusetts
“For”
Martine J. Piccart, Institut Jules Bordet, Brussels, Belgium
“Against”
Virginia F. Borges, University of Colorado Anshutz Medical Campus, Aurora, Colorado
State-of-the-Art Session 1: Immunotherapy— Purpose, Resistance, and Toxicity, Stars at Night Ballroom 3-4
Moderator: Sherene Loi, Peter MacCallum Cancer Centre, Melbourne, Australia
Biomarkers predicting immune related adverse events
Toni K. Choueiri, Dana-Farber Cancer Institute, Boston, Massachusetts
Cellular therapies: What is the outlook for breast and other solid cancers?
Valentina Hoyos Velez, Baylor College of Medicine, Houston, Texas
Tumor mechanisms of resistance to immunotherapy
Sherene Loi, Peter MacCallum Cancer Centre, Melbourne, Australia
Chromosomal instability and resistance to immunotherapy
Kevin Litchfield, University College London, London, England
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2:00 pm - 3:00 pm
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Molecular Tumor Board, Hemisfair Ballroom 1-2
Moderator: Pedram Razavi, Memorial Sloan Kettering Cancer Center, New York, New York
Panelists:
Giuseppe Curigliano, European Institute of Oncology, Milan, Italy
Gaorav Gupta, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Maryam Shirazi, Tempus Labs, Inc., Chicago, Illinois
Nancy U. Lin, Dana-Farber Cancer Institute, Boston, Massachusetts
Elizabeth A. Morris UC Davis School of Medicine, Sacramento, California
Joyce A. O'Shaughnessy, Baylor University Medical Center, Dallas, Texas
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3:00 pm - 3:10 pm |
BREAK |
3:10 pm - 5:00 pm
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CONCURRENT EDUCATIONAL SESSION BLOCK #2
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ED05: Controversies in Local Regional Management, Hemisfair Ballroom 1-2
Moderator: Debra Patt, Texas Oncology, Austin, Texas
Demystifying the axilla: Challenging scenarios in the upfront surgery setting and after neoadjuvant chemotherapy
Andrea V. Barrio, Memorial Sloan Kettering Cancer Center, New York, New York
When less is more: Patient-friendly radiation courses with WBI and PBI
Icro Meattini, Università degli Studi di Firenze, Florence, Italy
Surgical management of clinical stage I HER 2+ and triple negative breast cancer
Anita Mamtani, Memorial Sloan Kettering Cancer Center, New York, New York
Optimizing outcomes: Breast reconstruction technique and timing after mastectomy
Marco Maricevich, Baylor College of Medicine, Houston, Texas
Panelist: Jamie LaScala, Translational Center of Excellence in Breast Cancer, Penn Medicine, Philadelphia, Pennsylvania
ED06: Coordinated Care of Brain Metastasis, Hemisfair Ballroom 3
Moderator: Carey K. Anders, Duke University Comprehensive Cancer Center, Durham, North Carolina
Speakers:
Rebecca Dent, National Cancer Centre Singapore, Singapore
Christopher D. Lascola, Duke University Medical Center, Durham, North Carolina
Nelson Moss, Memorial Sloan Kettering Cancer Center, New York, New York
Helen A. Shih, Massachusetts General Hospital, Boston, Massachusetts
Jeffrey Wefel, UT MD Anderson Cancer Center, Houston, Texas
ED07: HER2+ Breast Cancer— Updates from the Clinic and the Lab, Stars at Night Ballroom 1-2
Moderator: Mothaffar F. Rimawi, Baylor College of Medicine, Houston, Texas
Molecular determinates of response and resistance in HER2+ breast cancer
Ron Bose, Washington University School of Medicine in St. Louis, St. Louis, Missouri
Recent advances in systemic disease
Sherene Loi, Peter MacCallum Cancer Centre, Melbourne, Australia
Management of brain metastases
Sarah L. Sammons, Dana-Farber Cancer Institute, Boston, Massachusetts
Panelist: Terlisa Sheppard, Terlisa Fights Breast Cancer, Inc., Florida
ED08: Toxicity Management— Next-Gen Therapies Means Next-Gen Toxicities, Stars at Night Ballroom 3-4
Moderator: Antonio C. Wolff, Johns Hopkins University, Baltimore, Maryland
Antibody drug conjugates
Heather L. McArthur, UT Southwestern Medical Center, Dallas, Texas
Targeted therapeutics in hormone positive breast cancers
Erica L. Mayer, Dana-Farber Cancer Institute, Boston, Massachusetts
Immunotherapies: short and long term
Douglas B. Johnson, Vanderbilt University Medical Center, Nashville, Tennessee
Panelist: Sheila Johnson, Komen Advocates in Science, Swansea, Illinois
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5:00 pm - 7:00 pm
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POSTER SESSION 2, Halls 2-3
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5:30 pm - 6:30 pm
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #3
PS7
Prevention, Stars at Night Ballroom 3-4
PS8 Antibody Drug Conjugates: Where are we headed? Hemisfair Ballroom 1-2
PS9 Exploiting Tumor Biology in HER2-positive Breast Cancer to
Escalate or De-escalate Neoadjuvant Therapy, Stars at Night Ballroom 1-2
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7:00 pm
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EXHIBITS CLOSE, Halls 2-3
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Thursday, December 7
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7:00 am - 8:00 am
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #4
PS10
Refining Prediction of Cancer Risk and Outcomes, Stars at Night Ballroom 3-4
PS11 CNS Disease in Breast Cancer: Where are We Now and Can We
do Better? Hemisfair Ballroom 1-2
PS12 Putting Brakes on the Cell Cycle: Understanding Mechanisms
Governing CDK 4/6 inhibitor Resistance and Role for Novel Therapeutic
Strategies, Stars at Night Ballroom 1-2
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8:00 am - 8:15 am
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BREAK
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8:15 am - 11:15 am
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General Session 2, Hall 1
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11:20 am - 11:50 am
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Plenary Lecture 1, Hall 1
Breast cancer evolution, immune evasion and metastasis driven by chromosomal instability
Charles Swanton, The Francis Crick Institute, London, England
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11:50 am - 12:00 pm
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BREAK
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12:00 pm
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EXHIBITS OPEN, Halls 2-3 |
12:00 pm - 2:00 pm
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POSTER SESSION 3, Halls 2-3
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1:00 pm - 1:30 pm
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AACR Distinguished Lectureship in Breast Cancer Research, supported by Aflac Inc., Stars at Night Ballroom 1-2
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1:00 pm - 2:00 pm
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CONCURRENT SESSIONS
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Clinical Case Discussions, Stars at Night Ballroom 3-4
Moderator: Matthew P. Goetz, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
Panelists:
Fabrice André, Gustave Roussy, Villejuif, France
Nadia Harbeck, LMU University Hospital, Munich, Germany
Erica L. Mayer, Dana-Farber Cancer Institute, Boston, Massachusetts
Aleix Prat, Hospital Clínic Barcelona, Barcelona, Spain
Hope S. Rugo, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
State-of-the-Art Session 2: Implications of Senescence for Breast Cancer Biology and Treatment, Hemisfair Ballroom 1-2
Moderator: Justin M. Balko, Vanderbilt University, Nashville, Tennessee
Cellular senescence: The Senescence-Associated Secretory Phenotype (SASP) and immunity
Marcus Ruscetti, UMass Chan Medical School, Worcester, Massachusetts
Implications of therapy induced senescence in breast cancer
James G. Jackson, Tulane University School of Medicine, New Orleans, Louisiana
Clinical trials and new therapeutics
Shom Goel, Peter MacCallum Cancer Centre, Melbourne, Australia
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2:00 pm - 3:00 pm
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Clinical Controversies, Stars at Night Ballroom 3-4
Moderator: Lisa A. Carey, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Are we ready to stop staging the axilla?
Monica Morrow, Memorial Sloan Kettering Cancer Center, New York, New York
Armando E. Giuliano, Cedars-Sinai Medical Center, Los Angeles, California
How to treat small triple negative breast cancer
Priyanka Sharma, University of Kansas Medical Center, Kansas City, Kansas
Alexandra Thomas, Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
Biology or stage? Tailoring treatment for premenopausal women with nodal involvement, but low oncotype
Eric P. Winer, Yale Cancer Center, New Haven, Connecticut
Kevin M. Kalinsky, Emory Winship Cancer Institute, Atlanta, Georgia
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3:00 pm - 3:10 pm |
BREAK |
3:10 pm - 5:00 pm
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CONCURRENT EDUCATIONAL SESSION BLOCK #3
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ED09: Genomics for Clinical Research and Cancer Care, Stars at Night Ballroom 1-2
Moderator: Norah Lynn Henry, Rogel Cancer Center University of Michigan, Ann Arbor, Michigan
Actionable mutations in breast cancer: Targeting the pathway
Milan Radovich, Caris Life Sciences, Irving, Texas
Tumor tissue vs. ctDNA
Ben O'Leary, Royal Marsden Hospital, London, England
When do you order and how to interpret genomic testing
Jorge S. Reis-Filho, Memorial Sloan Kettering Cancer Center, New York, New York
ED10: PI(3)king the Right Target, Stars at Night Ballroom 3-4
Moderator: Cynthia X. Ma, Washington University Siteman Cancer Center, Saint Louis, Missouri
PI3 Kinase
Neil Vasan, Columbia University Irving Medical Center, New York, New York
AKT pathway
Alex Toker, Beth Israel Deaconess Medical Center, Boston, Massachusetts
mTOR pathway
Robert J. Schneider, NYU Grossman School of Medicine, New York, New York
ED11: Inflammatory Breast Cancer: Clinical Challenges, Evolving Concepts and Novel treatments (People’s Choice), Hemisfair Ballroom 1-2
Moderator: Filipa Lynce, Dana-Farber Cancer Institute, Boston, Massachusetts
Is IBC a genomically different type of BC?
Frederick Howard, University of Chicago, Chicago, Illinois
Surgical controversies in IBC
Antony Lucci, UT MD Anderson Cancer Center, Houston, Texas
Approaches to radiation therapy in IBC
Jennifer Bellon, Dana-Farber Cancer Institute, Boston, Massachusetts
Panelists:
Terry Arnold, The IBC Network Foundation, Sealy, Texas
Ginny Mason, Inflammatory Breast Cancer Research Foundation, Broadway, Virginia
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5:00 pm - 7:00 pm
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POSTER SESSION 4, Halls 2-3
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5:30 pm - 6:30 pm
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #5
PS13
Special Populations: Pregnancy, Male and Geriatric Patients, Stars at Night Ballroom 3-4
PS14 Setting Expectations for Toxicities Related to I/O Therapy, Hemisfair Ballroom 1-2
PS15 Novel Nuclear Receptor Targeting Therapies, Stars at Night Ballroom 1-2
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7:00 pm
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EXHIBITS CLOSE, Halls 2-3
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Friday, December 8
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7:00 am - 8:00 am
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CONCURRENT POSTER SPOTLIGHT SESSIONS BLOCK #6
PS16
Enhancing Immunotherapy for Triple Negative Breast Cancer: Novel Therapies
and Biomarkers, Stars at Night Ballroom 3-4
PS17: Biomarkers of Response and/or Resistance to Endocrine
Based Therapies: Implications for Treatment Approaches, Hemisfair Ballroom 1-2
PS18 Disparate Care calls for Desperate Measures: Understanding Gaps in Quality of Care and
Opportunities to Improve it, Stars at Night Ballroom 1-2
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8:00 am - 8:15 am
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BREAK
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8:15 am - 11:15 am
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General Session 3, Hall 1
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11:15 am - 11:45 am
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Plenary Lecture 2, Hall 1
Recent advances in triple negative breast cancer
Melinda L. Telli, Stanford University School of Medicine, Stanford, California
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11:45 am - 12:00 pm
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BREAK
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12:00 pm
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EXHIBITS OPEN, Halls 2-3 |
12:00 pm - 2:00 pm
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POSTER SESSION 5, Halls 2-3
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1:00 pm - 1:30 pm
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AACR Outstanding Investigator Award for Breast Cancer Research, supported by the Breast Cancer Research Foundation, Stars at Night Ballroom 1-2
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1:30 pm - 2:30 pm
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CONCURRENT SESSIONS
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Translational Research Controversies, Stars at Night Ballroom 3-4
Moderator: Komal Jhaveri, Memorial Sloan Kettering Cancer Center, New York, New York
Per Hall, Karolinska Institutet, Stockholm, Sweden
Jack Cuzick, Queen Mary University of London, London, England
When to do a window trial
Mitchell Dowsett, Royal Marsden Hospital, London, England
Sara A. Hurvitz, UCLA – University of California Los Angeles, Los Angeles, California
Are we sequencing too late?
Charles M. Perou, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Fabrice André, Gustave Roussy, Villejuif, France
State-of-the-Art Session 3: Targeting Mutant ER, Hemisfair Ballroom 1-2
Moderator: Aditya Bardia, Massachusetts General Hospital, Boston, Massachusetts
Biological consequences of ESR1 mutation
Geoffrey L. Greene, University of Chicago, Chicago, Illinois
Tracking mutant ER using ctDNA
François-Clément Bidard, Institut Curie, Paris, France
The future of oral SERDs
Erika P. Hamilton, Sarah Cannon Research Institute, Nashville, Tennessee
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2:30 pm - 2:45 pm
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BREAK
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2:45 pm - 3:45 pm
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Year in Review, Hall 1
Moderator: Carlos L. Arteaga, UT Southwestern Harold C. Simmons Comprehensive Cancer Center, Dallas, Texas
Advanced Breast Cancer
Mariana Chavez-Mac Gregor, UT MD Anderson, Houston, Texas
Early Breast Cancer
Ann H. Partridge, Dana-Farber Cancer Institute, Boston, Massachusetts
Basic Science
Heide L. Ford, University of Colorado Denver School of Medicine, Denver, Colorado
Translational
Jennifer K. Richer, University of Colorado Anshutz Medical Campus, Aurora, Colorado
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3:45 pm - 4:00 pm
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BREAK
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4:00 pm
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Exhibits Close, Hall 2-3
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4:00 pm - 6:00 pm
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View from the Trenches: What will You do on Monday Morning? Hall 1
Moderator: Sara M. Tolaney, Dana-Farber Cancer Institute, Boston, Massachusetts
Panelists:
Javier Cortes Castan, Ramón y Cajal University Hospital, Madrid, Spain
Lesley Glenn, Project Life, Central Point, Oregon
Sara A. Hurvitz, University of California Los Angeles, Los Angeles, California
Joyce A. O'Shaughnessy, Baylor University Medical Center, Dallas, Texas
Richard C. Zellars, Indiana University School of Medicine, Indianapolis, Indiana
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Saturday, December 9
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8:00 am - 12:00 pm
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Career Development Forum
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8:00 am - 8:45 am |
Achieving Your Career Goals: Lessons from a
Successful Scientist, Stars at Night Ballroom 1-2
Moderator: Kate Lathrop, UT Health San Antonio MD Anderson
Cancer Center, San Antonio, TX
Speaker to be announced
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8:45 am - 9:00 am |
BREAK |
9:00 am - 11:00 am |
Concurrent Workshops for Early Career Scientists
(pre-registration required)
Planning Your First Clinical Trial, Room 302
This
workshop for residents, fellows, and early-stage clinical faculty will consist
of a 60-minute panel discussion with expert clinical trialists followed by
breakout into small groups for peer-to-peer evaluation of a clinical trial
concept.
Panelists:
Carole Baas, Alamo Breast Cancer Foundation, Southlake, Texas
Thomas Braun, University of Michigan, Ann Arbor, Michigan
Dawn L. Hershman, Columbia University Medical Center, New York, New York
Ruth O’Regan, University of Rochester, Rochester, New York
Additional panelists to be announced
Grant Writing
Tips and Tricks, Room 303
This
workshop for graduate students, fellows, and early-stage faculty will consist
of a 60-minute panel discussion with expert grant writers and reviewers
followed by breakout into small groups for peer-to-peer evaluation of a specific
aims page.
Panelists:
David Gius, Mays Cancer Center at UT Health San Antonio, San Antonio, Texas
Reuben S. Harris, UT Health San Antonio, San Antonio, Texas
Additional panelists to be announced
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9:00 am - 12:00 pm |
Navigating Success: Women’s Career Development (pre-registration required), Room 304
Designed for women who have completed
their traineeships, this workshop is a dynamic and inclusive event aimed to
inspire and support women pursuing careers in scientific research. The workshop
provides a platform for accomplished female scientists to share their
experiences, offer mentorship, and discuss strategies to overcome
gender-related challenges in the field. Through engaging talks, interactive
sessions, and networking opportunities, participants gain valuable insights,
build a strong support network, and acquire tools to thrive and excel in their
scientific research careers.
Setting the stage for success
Anne Welsh, Psychologist and Executive Coach,
Cambridge, Massachusetts
Evidence-based strategies to address systemic barriers facing women researchers
Reshma Jagsi, Emory University, Atlanta Georgia
Title to be announced
Amelie Ramirez, UT Health Sciences Center at San Antonio, San Antonio, Texas
Additional Speakers to be announced
Interactive Portion of Workshop
Anne Welsh,Psychologist and Executive Coach, Cambridge, Massachusetts
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11:00 am -12:00 pm |
Networking and Career Roundtable Discussions
(pre-registration required), Stars at Night Ballroom 1-2
The Networking and Career Roundtables provide interactive
informational interviews with experts on a variety of topics that are important
for career development. These discussions provide attendees with an opportunity
to speak face-to-face with colleagues and potential collaborators. Early career
investigators are encouraged to participate for the opportunity to meet
respected senior investigators and connect with researchers of similar
interests. Light refreshments will be provided. Topics and mentors to be announced.
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