Working titles shown. Final titles will be announced.
Wednesday, December 8, 2010
2:00 PM - 7:30 PM
EDUCATIONAL SESSIONS
Ballroom C
An update on advances in the technologies available for translational research. Sessions are to provide people with a better understanding of the talks they hear using the techniques described. They also provide researchers with a guide to the techniques they should be considering for their studies.
CNS Metastases in Breast Cancer: Current Challenges and Future Directions
Moderator: Nancy U. Lin, MD
Dana-Farber Cancer Institute
Boston, MA
Advances in neurosurgery in the management of CNS metastases
Elizabeth B. Claus, MD, PhD
Yale University
New Haven, CT
Radiation therapy for CNS metastases: What should the standard approach be?
Minesh P. Mehta, MD
University of Wisconsin School of Medicine and Public Health
Madison, WI
Systemic therapy for CNS metastases
Nancy U. Lin, MD
Dana-Farber Cancer Institute
Boston, MA
Translating new approaches from bench to bedside
Patricia S. Steeg, PhD
National Cancer Institute
Bethesda, MD
Panel Discussion
The Clinical Utility of Genetic Testing for Inherited Predisposition to Breast Cancer: BRCA and Beyond
Moderator: Mark E. Robson, MD
Memorial Sloan-Kettering Cancer Center
New York, NY
Evaluation of breast cancer predisposition in different clinical venues
Sharon E. Plon, MD, PhD
Baylor College of Medicine
Houston, TX
Management of women with a highly penetrant predisposition to breast cancer: State of the art 2010
Susan M. Domchek, MD
University of Pennsylvania
Philadelphia, PA
Challenges to clinical application of new discoveries in the genetics of breast cancer predisposition
Mark E. Robson, MD
Memorial Sloan-Kettering Cancer Center
New York, NY
Emerging Radiation Techniques – The Fast and the Furious
Moderator: Richard L. Crownover, MD, PhD
UT Health Science Center San Antonio
San Antonio, TX
Rationale and results of accelerated partial breast irradiation
Frank A. Vicini, MD, FACR
William Beaumont Hospital
Royal Oak, MI
Radiosurgery and stereotactic body radiotherapy
Richard L. Crownover, MD, PhD
UT Health Science Center San Antonio
San Antonio, TX
Symptom Management
Moderator: Laura J. Esserman, MD, MBA
University of California San Francisco
San Francisco, CA
Balancing risks of deconditioning vs. weight-lifting for breast cancer survivors for Lymphedema
Kathryn H. Schmitz, PhD, MPH
University of Pennsylvania School of Medicine
Philadelphia, PA
Understanding the role of botanicals in the management of breast cancer
Debasish Tripathy, MD
University of Southern California
Los Angeles, CA
Long term management of pain due to, and after, primary treatment of breast cancer
Michael W. Rabow, MD
University of California San Francisco
San Francisco, CA
Losing your hair during chemotherapy may not be inevitable: emerging techniques to avoid hair loss
Hope S. Rugo, MD
University of California San Francisco
San Francisco, CA
Design & Interpretation of Biomarker Studies
Moderator: Mitchell Dowsett, MD, PhD
Royal Marsden Hospital NHS Trust
London, UNITED KINGDOM
Statistical challenges in predictive and prognostic biomarker studies: How to avoid wasting your time and specimens
Lisa M. McShane, PhD
National Cancer Institute
Bethesda, MD
The importance of technical validation
Jorge Reis-Filho
, MD, PhD, MRCPath
Breakthrough Breast Cancer Research Center
The Institute of Cancer Research
London, UNITED KINGDOM
Interpretation of biomarker studies
Lajos Pusztai, MD, DPhil
UT MD Anderson Cancer Center
Houston, TX
DNA Repair
Moderator: Daniel P. Silver, MD, PhD
Dana-Farber Cancer Institute
Boston, MA
DNA repair pathways and tumorigenesis
James M. Ford, MD
Stanford University Medical Center
Stanford, CA
DNA repair and breast cancer: Therapeutic opportunities and challenges
Daniel P. Silver, MD, PhD
Dana-Farber Cancer Institute
Boston, MA
Automated, Quantitative Cell and Tissue Imaging Technologies
Moderator: Rachel Schiff, PhD
Baylor College of Medicine
Houston, TX
Measuring and modeling cell death pathways in tumor cells
Peter K. Sorger, PhD
Harvard Medical School
Boston, MA
Quantitative methods to assess eligibility for breast cancer therapy
David L. Rimm, MD, PhD
Yale University School of Medicine
New Haven, CT
Next Generation Sequencing for the Clinician
Moderator: Charles M. Perou, PhD
University of North Carolina
Chapel Hill, NC
Next-generation sequencing and analysis of tumor/normal pairs
Elaine R. Mardis, PhD
Washington University
St. Louis, MO
Leveraging next generation sequencing in the study of breast cancer somatic genetics
Andrew Futreal, PhD
Wellcome Trust Sanger Institute
Cambridge, UNITED KINGDOM
Next generation sequencing for gene expression profiling
Charles M. Perou, PhD
University of North Carolina
Chapel Hill, NC
Systems Biology – Can it Explain Everything?
Moderator: Adrian V. Lee, PhD
University of Pittsburgh Cancer Institute
Pittsburgh, PA
Cancer systems biology: Concepts and perspectives?
Douglas A. Lauffenburger, PhD
Massachusetts Institute of Technology
Cambridge, MA
Modeling sensitivity to therapeutic agents
Paul T. Spellman, PhD
Lawrence Berkeley National Laboratory
Berkeley, CA
Systems biology for the clinician
Dana Faratian, MD,
FRCPath
Edinburgh Breakthrough Research Unit
University of Edinburgh
Edinburgh, UNITED KINGDOM
AWARD LECTURES
Exhibit Hall D
AACR Outstanding Investigator Award for Breast Cancer Research, funded by Susan G. Komen for the Cure®
Speaker and Title TBA
AACR Distinguished Lectureship in Breast Cancer Research
Synthetic Lethal Approaches to Cancer Therapy
Alan Ashworth, PhD, FMedSci, FRS
Breakthrough Research Centre at
The Institute of Cancer Research
London, UNITED KINGDOM
William L. McGuire Memorial Lecture
What Would Bill Do? Channeling Your Inner McGuire
George W. Sledge, Jr., MD
Indiana University Simon Cancer Center
Indianapolis, IN
Susan G. Komen for the Cure Brinker Awards for Scientific Distinction Lectures
Speakers and Titles TBA
PLENARY LECTURES
Exhibit Hall D
Metabolic Reprogramming of Cancer Cells and Therapeutic Opportunities
Chi Van Dang, MD, PhD
Johns Hopkins University School of Medicine
Baltimore, MD
Drug Development – Targeting HER2 Beyond Trastuzumab
Neil L. Spector, MD
Duke University Medical Center
Durham, NC
The Upside of Irrationality
Dan Ariely, PhD
Duke University
Durham, NC
MINI-SYMPOSIA
Exhibit Hall D
noncodingRNA - The New Frontier
Moderator: Saraswati Sukumar, PhD
Johns Hopkins University School of Medicine
Baltimore, MD
Long noncoding RNAs in breast cancer progression
Howard Y. Chang, MD, PhD
Stanford University School of Medicine
Stanford, CA
MicroRNA in medical practice
George A. Calin, MD, PhD
UT MD Anderson Cancer Center
Houston, TX
Surgery
Moderator: Ismail Jatoi, MD, PhD, FACS
UT Health Science Center San Antonio
San Antonio, TX
Surgical considerations in early-stage breast cancer
Lisa A. Newman, MD, MPH, FACS
University of Michigan Medical School
Ann Arbor, MI
Recent U.S. trends in the local treatment of primary breast cancer
Todd M. Tuttle, MD, MPH
University of Minnesota
Minneapolis, MN
Nipple sparing mastectomy with intra operative radiotherapy
Jean-Yves Petit
European Institute of Surgical Oncology
Milan, ITALY
Breast Cancer Health Disparities
Moderator: Amelie G. Ramirez, Dr. PH, MPH
UT Health Science Center San Antonio
San Antonio, TX
Advance in breast cancer risk assessment screening and prevention: Adapting the lessons to an underserved Latin population
Jeffrey N. Weitzel, MD
City of Hope National Medical Center
Duarte, CA
The role of providers in breast cancer disparities
Nancy L. Keating, MD, MPH
Harvard Medical School
Boston, MA
African ancestry and high-risk breast cancer
Lisa A. Newman, MD, MPH, FACS
University of Michigan Medical School
Ann Arbor, MI
THE YEAR IN REVIEW
Sunday, December 12, 2010
Exhibit Hall D
Moderator: C. Kent Osborne, MD
Baylor College of Medicine
Houston, TX
Advances in basic breast cancer research
Suzanne A.W. Fuqua, PhD
Baylor College of Medicine
Houston, TX
Translational breast cancer research
Mitchell Dowsett, MD, PhD
Royal Marsden Hospital NHS Trust
London, UNITED KINGDOM
Early breast cancer
Aron Goldhirsch, MD
European Institute of Oncology
Milan, ITALY
Progress in advanced breast cancer
Lisa A. Carey, MD
University of North Carolina
Chapel Hill, NC
BASIC SCIENCE FORUMS - Lunchtime Sessions
Ballroom B
Stem Cells - Defying Definition?
Moderator: Jorge Reis-Filho, MD, PhD, MRCPath
Breakthrough Breast Cancer Research Center
The Institute of Cancer Research
London, UNITED KINGDOM
Stem cells and cancer, 2 faces of self renewal
Michael F. Clarke, MD
Stanford University School of Medicine
Stanford, CA
Understanding stem cells to get abreast of breast cancer
Geoffrey J. Lindeman,
MD, PhD
The Walter and Eliza Hall Institute of Medical Research
Parkville, AUSTRALIA
Managing Stress in Cancer Cells: New Druggable Pathways and Targets
Moderator: C. Kent Osborne, MD
Baylor College of Medicine
Houston, TX
Cancers are stressed too: exploiting cancer stress for new therapies
Garth Powis, D.Phil.
UT MD Anderson Cancer Center
Houston, TX
Molecular chaperones: Cancer dependence and druggability
Paul Workman, PhD, DSc (Hon), FMedSci FSB
Cancer Research UK Centre of Cancer Therapeutics
The Institute Of Cancer Research
Sutton, UNITED KINGDOM
Breast Cancer Recurrence and Tumor Dormancy – What is it? Does it matter?
Moderator: Lewis A. Chodosh, MD, PhD
University of Pennsylvania School of Medicine
Philadelphia, PA
Models to mechanisms: Understanding tumor dormancy and breast cancer recurrence
Lewis A. Chodosh, MD, PhD
University of Pennsylvania School of Medicine
Philadelphia, PA
TBA
CLINICAL SCIENCE FORUM - Lunchtime Sessions
Ballroom A
Controversies in Screening for Breast Cancer
Moderator: Eric P. Winer, MD
Dana-Farber Cancer Institute
Boston, MA
Rethinking and improving screening in the context of breast cancer biology
Laura J. Esserman, MD, MBA
University of California San Francisco
San Francisco, CA
Breast cancer screening – The radiology perspective
Chris I. Flowers, MBBS
University of California San Francisco
San Francisco, CA
Panel Discussion
Laura J. Esserman, MD, MBA
University of California San Francisco
San Francisco, CA
Chris I. Flowers, MBBS
University of California San Francisco
San Francisco, CA
Judy E. Garber, MD, MPH
Dana-Farber Cancer Institute
Boston, MA
Chris Tannous, PhD
Susan G. Komen for the Cure
Fountain Valley, CA
CASE DISCUSSIONS - Lunchtime Sessions
Ballroom A
CAREER DEVELOPMENT FORUM
Ballroom A
The session is open to early-career scientists, defined as graduate students, postdoctoral or clinical fellows, or medical students and residents, who are registered attendees of the SABCS. Space in the workshop is limited to 135 participants; registrations will be accepted on a first-come, first-served basis and is free of charge. Registration information will be available in mid-2010.
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